Pittsburgh vs. Louisville
Record against Louisville since 1988: 2-3
Last home loss against Louisville: November 25, 2006Last road win against Louisville: October 02, 2009
| Season | Outcome | Location |
|---|---|---|
| 2010 | October 30, 2010 | Home |
| 2009 | Win, 35-10 (see details) | Away |
| 2008 | Win, 41-7 (see details) | Home |
| 2007 | Loss, 17-24 (see details) | Away |
| 2006 | Loss, 24-48 (see details) | Home |
| 2005 | Loss, 20-42 (see details) | Away |