Southern Mississippi vs. Louisiana-Lafayette
Record against Louisiana-Lafayette since 1988: 3-0
Last road win against Louisiana-Lafayette: September 22, 2001| Season | Outcome | Location |
|---|---|---|
| 2008 | Win, 51-21 (see details) | Home |
| 2003 | Win, 48-3 (see details) | Home |
| 2001 | Win, 35-10 (see details) | Away |